The study examined the extent to which pay satisfaction predicted the quality of life among teachers in Gokana area of Rivers State. It also investigated the role of gender differences in the quality of life among teachers in senior secondary schools in Gokana local government a r e a of Rivers State. The study adopted the descriptive survey design. Purposive sampling technique was used to select the schools and teachers. Two standardized psychological instruments namely: Pay Satisfaction Questionnaire (PSQ) and “Quality of Life” (QOL) were used to collect the data for the study. The study shows that pay satisfaction significantly and independently predicts quality of life among teachers (β = .66, t = 12.57, p<.05). The contribution of pay satisfaction in explaining the variance in quality of life was 44% (R2= .44), and the model was significant, F(1, 198) = 158.18, p<.05. The study also revealed that there was a significant gender difference on the quality of life t(198) = -2.11, p<.05. This means that female teachers (Mean=54.09, SD= 7.91) have higher quality of life than their male counterpart (Mean=51.59, 8.74). The study concluded that pay satisfaction predicted the quality of life of teachers, while pay satisfaction and gender independently and jointly predicted the quality of life of teachers in selected schools in Gokana area of Rivers State. The research, therefore, recommends, among other things, that teachers' conditions of service should improve with an increase in salaries. This will boost productivity and improve the teachers' quality of life.